| Vorliegende Sprache |
eng |
| Hinweise auf parallele Ausgaben |
371084733 Buchausg. u.d.T.: ‡Öisjöen, Fredrik, 1982 - : High-Tc SQUIDs for biomedical applications |
| ISBN |
978-3-642-31355-4 |
| Name |
Öisjöen, Fredrik |
| T I T E L |
High-Tc SQUIDs for Biomedical Applications: Immunoassays, Magnetoencephalography, and Ultra-Low Field Magnetic Resonance Imaging |
| Verlagsort |
Berlin, Heidelberg |
| Verlag |
Springer |
| Erscheinungsjahr |
2013 |
| 2013 |
| Umfang |
Online-Ressource (XVIII, 97 p. 67 illus., 28 illus. in color, digital) |
| Reihe |
Springer Theses, Recognizing Outstanding Ph.D. Research |
| Notiz / Fußnoten |
Description based upon print version of record |
| Weiterer Inhalt |
High-Tc SQUIDs for Biomedical Applications:Immunoassays,Magnetoencephalography,and Ultra-Low Field Magnetic Resonance Imaging; Supervisor's Foreword; Acknowledgments; Contents; Symbols and Abbreviations; Abbreviations; 1 Introduction; References; 2 High-Tc SQUIDs; 2.1 The Josephson Effect; 2.2 The dc SQUID; 2.2.1 Noise in dc SQUIDs; 2.2.2 SQUID Readout; 2.2.3 SQUID Considerations; 2.2.4 Device Layout; 2.3 Device Fabrication; 2.3.1 Thin Film Deposition; 2.3.2 Thin Film Processing; 2.4 SQUID Performance; References; 3 Magnetic Immunoassays; 3.1 Introduction; 3.1.1 Antibodies and Antigens. 3.1.2 ELISA Protocols3.2 Magnetic Nanoparticles; 3.2.1 General Aspects; 3.2.2 Magnetic Anisotropy; 3.2.3 Size Distribution; 3.2.4 Magnetic Relaxation; 3.2.5 Superparamagnetism; 3.3 Experimental Methods; 3.3.1 Experimental Setup; 3.3.2 Measurement Techniques; 3.3.3 Assay Experiments; 3.4 Results and Discussion; 3.4.1 System Verification and Calibration; 3.4.2 Assay Experiments; 3.4.3 Aging of Functionalized MNPs; References; 4 Magnetoencephalography; 4.1 Introduction; 4.2 The Human Brain and Neurons; 4.3 Disturbances and Artifacts; 4.4 Experimental Methods. 4.4.1 Experimental Setup and Protocol4.4.2 Two-Channel MEG; 4.5 Results and Discussion; 4.5.1 Simulations; 4.5.2 Brain Activity Recordings; References; 5 Ultra Low Field Magnetic Resonance Imaging; 5.1 Introduction; 5.2 Basic Concepts of MRI; 5.3 NMR/MRI in Ultra Low Fields Using SQUIDs; 5.4 Experimental Methods; 5.4.1 Experimental Setup; 5.4.2 Coil Design; 5.5 Results and Discussion; 5.5.1 Free Induction Decay and T1; 5.5.2 1-D Gradient; 5.6 Issues and Future Work; References; 6 Conclusions; 6.1 Outlook and Discussion; References; |
| Titelhinweis |
Buchausg. u.d.T.: ‡Öisjöen, Fredrik, 1982 - : High-Tc SQUIDs for biomedical applications |
| ISBN |
ISBN 978-3-642-31356-1 |
| ISBN 1-283-63127-X ebk |
| ISBN 978-1-283-63127-3 MyiLibrary |
| Klassifikation |
TDPB |
| TEC027000 |
| 620.5 |
| T174.7 |
| Kurzbeschreibung |
This thesis describes the challenging task of developing high critical temperature superconducting quantum interference devices (high-Tc SQUIDs) and using them as sensors for biomedical applications, including magnetic immunoassays, magnetoencephalography and magnetic resonance imaging (MRI). The first part of this work discusses the development of fast magnetic immunoassays, which can be used to improve the sensitivity, or to create new, unique point-of-care diagnostics systems. The second part shows that high-Tc SQUIDs might make magnetoencephalography more available, thus opening the field of high-Tc SQUID-based magnetoencephalography for recording brain functions. This technique can be combined with ultra-low field MRI which is discussed in the last part. This combination may provide a new unique tool for studies of brain functions. This work does not simply improve on existing technology but opens possibilities for novel advanced medical devices and techniques. |
| 1. Schlagwortkette |
Quanteninterferometer |
| Detektor |
| Magnetoencephalographie |
| Kernspintomografie |
| 1. Schlagwortkette ANZEIGE DER KETTE |
Quanteninterferometer -- Detektor -- Magnetoencephalographie -- Kernspintomografie |
| 2. Schlagwortkette |
Immunassay |
| Markierung <Chemie> |
| Nanopartikel |
| Magnetwerkstoff |
| Detektion |
| Quanteninterferometer |
| 2. Schlagwortkette ANZEIGE DER KETTE |
Immunassay -- Markierung -- Nanopartikel -- Magnetwerkstoff -- Detektion -- Quanteninterferometer |
| 3. Schlagwortkette |
Quanteninterferometer |
| Detektor |
| Magnetoencephalographie |
| Kernspintomografie |
| ANZEIGE DER KETTE |
Quanteninterferometer -- Detektor -- Magnetoencephalographie -- Kernspintomografie |
| 4. Schlagwortkette |
Immunassay |
| Markierung <Chemie> |
| Nanopartikel |
| Magnetwerkstoff |
| Detektion |
| Quanteninterferometer |
| ANZEIGE DER KETTE |
Immunassay -- Markierung -- Nanopartikel -- Magnetwerkstoff -- Detektion -- Quanteninterferometer |
| SWB-Titel-Idn |
373364334 |
| Signatur |
Springer E-Book |
| Bemerkungen |
Elektronischer Volltext - Campuslizenz |
| Elektronische Adresse |
$uhttp://dx.doi.org/10.1007/978-3-642-31356-1 |
| Internetseite / Link |
Volltext |
| Siehe auch |
Volltext |
| Siehe auch |
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